The Key Facts About CAS 1169630-82-3 Semaglutide Intermediate
The Key Facts About CAS 1169630-82-3 Semaglutide Intermediate
Introduction to CAS 1169630-82-3 Semaglutide intermediateCAS 1169630-82-3 is a specific chemical compound that serves as an intermediate in the synthesis of Semaglutide, a medication used to treat type 2 diabetes. This compound plays a crucial role in the production process of Semaglutide, a highly effective glucagon-like peptide 1 (GLP-1) receptor agonist.The Importance of SemaglutideSemaglutide is a breakthrough medication that helps control blood sugar levels in people with type 2 diabetes. It works by stimulating insulin production and reducing glucose production in the liver. The use of Semaglutide has shown significant improvements in glycemic control and weight management in diabetic patients.Chemical Properties of CAS 1169630-82-3CAS 1169630-82-3 Semaglutide intermediate has a specific molecular structure and composition that are crucial for its role in the synthesis of Semaglutide. Understanding its chemical properties is essential for the successful production of Semaglutide.Synthesis Process of SemaglutideCAS 1169630-82-3 is a key intermediate compound in the multi-step synthesis process of Semaglutide. This compound undergoes various chemical reactions and transformations to eventually yield the final product, Semaglutide.Quality Control in Semaglutide ProductionThe use of CAS 1169630-82-3 in the synthesis of Semaglutide requires strict quality control measures to ensure the purity and efficacy of the final product. Quality control processes play a vital role in maintaining the safety and effectiveness of Semaglutide.Applications of Semaglutide in Diabetes TreatmentSemaglutide has gained widespread popularity in the treatment of type 2 diabetes due to its effectiveness in controlling blood sugar levels and promoting weight loss. This medication offers diabetic patients a valuable treatment option to manage their condition.Research and Development of SemaglutideOngoing research and development efforts are focused on exploring the potential benefits of Semaglutide in other therapeutic areas beyond diabetes. The versatility of this medication holds promise for future applications in related medical fields.Market Trends and Demand for SemaglutideThe growing prevalence of type 2 diabetes worldwide has fueled the demand for effective medications like Semaglutide. Market trends indicate a rising need for innovative treatments that can offer improved outcomes for diabetic patients.Regulatory Considerations for Semaglutide ProductionThe production and distribution of Semaglutide, including its intermediate compound CAS 1169630-82-3, are subject to stringent regulatory oversight to ensure compliance with standards for safety, quality, and efficacy. Regulatory considerations play a crucial role in the pharmaceutical industry.Future Prospects of CAS 1169630-82-3 Semaglutide IntermediateAs research and development in the field of diabetes treatment continue to advance, the role of CAS 1169630-82-3 as a key intermediate in Semaglutide synthesis will remain essential. The future prospects of this compound look promising for its continued contribution to innovative pharmaceutical solutions.Quote InquiryContact us!
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The Role of Semaglutide Side Chain (CAS Number: 1118767-16-0) in Medicinal Chemistry
The Role of Semaglutide Side Chain (CAS Number: 1118767-16-0) in Medicinal Chemistry
The Basics of Semaglutide Side ChainSemaglutide Side Chain, with CAS Number: 1118767-16-0, is an important component in the development of pharmaceuticals. It plays a crucial role in medicinal chemistry by influencing the properties and functions of drugs.Chemical Structure and CompositionThe chemical structure of Semaglutide Side Chain is characterized by a specific arrangement of atoms and functional groups. Its composition imparts unique characteristics to pharmaceutical compounds, affecting their efficacy and safety.Synthesis and ProductionSemaglutide Side Chain is synthesized through complex chemical reactions in laboratory settings. Its production involves precise techniques to ensure purity and quality, meeting the standards for pharmaceutical applications.Biological Activity and Mechanism of ActionWhen incorporated into drugs, Semaglutide Side Chain exhibits specific biological activity and interacts with target molecules in the body. Understanding its mechanism of action is essential for designing effective medications.Clinical Applications and Therapeutic UsesPharmaceuticals containing Semaglutide Side Chain have various clinical applications and therapeutic uses. They are utilized in the treatment of specific medical conditions, offering benefits to patients.Pharmacokinetics and PharmacodynamicsThe pharmacokinetics and pharmacodynamics of Semaglutide Side Chain determine how drugs are absorbed, distributed, metabolized, and excreted in the body. These aspects influence the drug's effectiveness and duration of action.Safety Profile and Side EffectsWhile Semaglutide Side Chain contributes to the potency of medications, it may also be associated with certain side effects. Understanding its safety profile is crucial for minimizing adverse reactions and ensuring patient well-being.Regulatory Considerations and Quality ControlRegulatory authorities impose stringent guidelines for the use of Semaglutide Side Chain in pharmaceutical products. Quality control measures are implemented to guarantee the purity, potency, and stability of drugs containing this component.Future Perspectives and Research DirectionsOngoing research on Semaglutide Side Chain aims to explore new applications, improve drug formulations, and enhance therapeutic outcomes. Future perspectives may reveal additional benefits and innovative uses of this key ingredient.ConclusionIn conclusion, Semaglutide Side Chain (CAS Number: 1118767-16-0) plays a vital role in the field of medicinal chemistry, contributing to the development of effective and safe pharmaceuticals. Its diverse applications and complex interactions make it a valuable component in drug discovery and therapy.Quote InquiryContact us!
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Discovering Advantages of Advantame 714229-20-6: A Comprehensive Guide
Discovering Advantages of Advantame 714229-20-6: A Comprehensive Guide
What is Advantame 714229-20-6?Advantame 714229-20-6 is a high-intensity sweetener that is derived from aspartame. It is a white, crystalline powder with a clean, sweet taste.Advantame 714229-20-6 - The AdvantagesAdvantame 714229-20-6 has many advantages over other sweeteners in the market. Some of them are:Sweetness to Calorie RatioAdvantame 714229-20-6 has a sweetness level that is 20,000 times more than sugar, which means you only need a very small quantity of it to sweeten your food or beverage. Moreover, compared to sugar, it has zero calories, making it a great option for those who want to reduce calorie intake.StabilityAdvantame 714229-20-6 is stable under high temperature, which means it is great for baking and cooking. It also has a long shelf life, making it a cost-effective option in the food industry.TasteAdvantame 714229-20-6 has a clean, sweet taste with no aftertaste or bitterness. This makes it an excellent choice for those who want to enjoy the sweetness in their food and beverages without any lingering aftertaste.Use in Food and BeveragesAdvantame 714229-20-6 can be used in a wide range of food and beverages, including soft drinks, baked goods, confectionery, and dairy products. It is also approved by the FDA, making it a safe option for consumption.How does Advantame 714229-20-6 compare to other Sweeteners?Advantame 714229-20-6 has many advantages when compared to other sweeteners. Here are some of the comparisons:Advantame 714229-20-6 Vs. AspartameAspartame is also a high-intensity sweetener, but it has a shorter shelf life and loses sweetness when exposed to heat. Advantame 714229-20-6 is more stable and can withstand high temperatures, making it a better option for cooking and baking.Advantame 714229-20-6 Vs. SucraloseSucralose is another zero-calorie sweetener that is commonly used in the food industry. While it has a longer shelf life than aspartame, it has a bitter aftertaste, which can affect the taste of the food and beverages that it is used in. Advantame 714229-20-6, on the other hand, has no aftertaste or bitterness, making it a preferable option for those who want a clean, sweet taste.The Safety of Advantame 714229-20-6Advantame 714229-20-6 has been approved by the FDA and is considered safe for consumption. It has also been approved by the European Food Safety Authority (EFSA), the Joint FAO/WHO Expert Committee on Food Additives (JECFA), and other regulatory agencies around the world.ConclusionAdvantame 714229-20-6 is a great option for those who want to enjoy the sweetness in their food and beverages without the added calories. It has many advantages over other sweeteners, including a high sweetness-to-calorie ratio, stability, and a clean, sweet taste. Moreover, it is safe for consumption and can be used in a wide range of food and beverages. This makes Advantame 714229-20-6 a great alternative for those who want to reduce their calorie intake, without sacrificing taste.Quote InquiryContact us!
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CAS 479-41-4 - Indirubin: What You Should Know
CAS 479-41-4 - Indirubin: What You Should Know
IntroductionIndirubin is a compound that is found in several plants and has been shown to have potential therapeutic benefits. One specific form of indirubin, known as CAS 479-41-4 - Indirubin, has been the subject of many research studies due to its unique properties. In this article, we will explore what CAS 479-41-4 - Indirubin is, how it works, and its potential benefits.What is CAS 479-41-4 - Indirubin?CAS 479-41-4 - Indirubin is a specific form of indirubin that is often used in research studies due to its purity and consistency. It is a dark red to purple powder and is soluble in alcohol and dimethyl sulfoxide. It has been shown to inhibit various cellular signaling pathways and has potential therapeutic effects.How Does CAS 479-41-4 - Indirubin Work?CAS 479-41-4 - Indirubin works by inhibiting various cellular signaling pathways, including the Wnt/β-catenin pathway and the JAK/STAT pathway. The Wnt/β-catenin pathway is involved in cell proliferation and differentiation, and dysregulation of this pathway is associated with various diseases, including cancer. The JAK/STAT pathway is involved in immune responses and is also dysregulated in various diseases. By inhibiting these pathways, CAS 479-41-4 - Indirubin may have potential therapeutic benefits.Potential Benefits of CAS 479-41-4 - IndirubinCAS 479-41-4 - Indirubin has been shown to have potential therapeutic benefits in various animal and cellular studies. Some of these potential benefits include:Anti-inflammatory effectsAnticancer effectsAntioxidant effectsNeuroprotective effectsAnti-Inflammatory EffectsInflammation is a natural response of the body to injury and infection. However, chronic inflammation is associated with various diseases, including cardiovascular disease, autoimmune diseases, and neurodegenerative diseases. CAS 479-41-4 - Indirubin has been shown to have anti-inflammatory effects by inhibiting various cytokines and enzymes involved in the inflammatory response.Anticancer EffectsCAS 479-41-4 - Indirubin has been shown to have anticancer effects in various animal and cellular studies. It has been shown to inhibit various signaling pathways involved in cell growth and differentiation, including the Wnt/β-catenin pathway and the AKT pathway. It has also been shown to induce apoptosis, or programmed cell death, in cancer cells.Antioxidant EffectsOxidative stress is associated with various diseases, including cardiovascular disease, neurodegenerative diseases, and cancer. CAS 479-41-4 - Indirubin has been shown to have antioxidant effects by reducing reactive oxygen species and increasing the activity of antioxidant enzymes.Neuroprotective EffectsCAS 479-41-4 - Indirubin has also been shown to have potential neuroprotective effects. It has been shown to protect against neurotoxicity induced by various compounds and to improve cognitive function in animal models of Alzheimer's disease and Parkinson's disease.Side Effects of CAS 479-41-4 - IndirubinThere is limited information on the side effects of CAS 479-41-4 - Indirubin. However, some studies have reported mild gastrointestinal side effects and changes in liver function tests in animal models.ConclusionCAS 479-41-4 - Indirubin is a specific form of indirubin that has potential therapeutic benefits. It works by inhibiting various cellular signaling pathways and has been shown to have anti-inflammatory, anticancer, antioxidant, and neuroprotective effects. While there is limited information on its side effects, it shows promise as a potential therapeutic agent.Quote InquiryContact us!
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Entercavir Hydrate 209216-23-9: Uses, Benefits and Side Effects
Entercavir Hydrate 209216-23-9: Uses, Benefits and Side Effects
The Intriguing Aspects of Entercavir Hydrate 209216-23-9Entercavir Hydrate 209216-23-9 is a remarkable medicine that is used in the treatment of Hepatitis B. It belongs to a class of antiviral medications known as nucleoside reverse transcriptase inhibitors (NRTIs). Entercavir Hydrate is a highly potent and selective drug that targets the hepatitis B virus. This article will discuss the benefits, uses and possible side effects of Entercavir Hydrate 209216-23-9.1. What is Entercavir Hydrate 209216-23-9?Entercavir Hydrate 209216-23-9 is a white to off-white crystalline powder. It is an orally administered antiviral drug that inhibits the reverse transcriptase enzyme of Hepatitis B. The medication is commonly sold in the form of tablets like Baraclude and Teva-Entecavir, for the treatment of chronic Hepatitis B virus infection. The drug functions by inhibiting the viral DNA synthesis, which leads to a drastic reduction in viral load in the liver and a decrease in the risk of developing liver damage.2. What Are The Uses of Entercavir Hydrate 209216-23-9?Entercavir Hydrate 209216-23-9 is an effective medication for the treatment of Hepatitis B. It helps to lower the amount of Hepatitis B virus in the body by blocking the replication of the virus. The drug is known to reduce the risk of liver damage, liver cancer and other associated liver disorders that may arise from chronic hepatitis B. Entercavir Hydrate 209216-23-9 may be prescribed as a primary treatment or as a supplementary treatment in combination with other antiviral medications.3. How Does Entercavir Hydrate Work?Entercavir Hydrate 209216-23-9 works by blocking the reverse transcriptase enzyme of Hepatitis B. This enzyme is responsible for the conversion of viral RNA to DNA, which is a critical step in the reproduction of the virus. Entercavir Hydrate 209216-23-9 inhibits this step and prevents the virus from replicating, thus reducing the viral load in the body.4. Who Can Benefit from Entercavir Hydrate 209216-23-9?Entercavir Hydrate 209216-23-9 is ideal for individuals who suffer from chronic Hepatitis B virus infection. It is effective in reducing the viral load and preventing the development of liver damage, liver cancer and other related liver disorders. However, individuals who have previously been infected with Hepatitis B and have recovered may not need the use of Entercavir Hydrate 209216-23-9.5. How Should Entercavir Hydrate Be Taken?Entercavir Hydrate 209216-23-9 should be taken orally, either on an empty stomach, or at least two hours after a meal. The dosage will be prescribed by the doctor based on the individual's medical condition, age, weight and other factors. It is crucial to take the medication regularly, at the same time every day, to maximize its benefits. Do not stop taking the drug without consulting with your doctor, as this may lead to a reoccurrence of the Hepatitis B virus.6. Can Entercavir Hydrate Be Taken During Pregnancy and Breastfeeding?Currently, there is limited information available on Entercavir Hydrate's effect on pregnancy and breastfeeding. It is advised that expecting mothers, those who are breastfeeding and those hoping to conceive, should consult with their doctors and discuss the potential risks and benefits of taking Entercavir Hydrate.7. What Are The Precautions to be Taken While Using Entercavir Hydrate?Before taking Entercavir Hydrate 209216-23-9, inform your doctor if you are allergic to any of its components. Let your healthcare provider know if you are currently taking any medications, as they may interact with Entercavir Hydrate, leading to unwanted side effects. Individuals with liver or kidney problems should not use Entercavir Hydrate without the advice of a doctor. Additionally, individuals with a history of HIV infection should use Entercavir Hydrate with caution, as it may increase their risk of developing resistance to HIV medications.8. How Is Entercavir Different from Other Hepatitis B medications?Compared to other medications that treat Hepatitis B, Entercavir Hydrate has a higher potency and a lower risk of creating resistance to Hepatitis B virus mutations. The drug is considered a first-line treatment for Hepatitis B virus infection and has proven to be effective in reducing the risk of cirrhosis, liver cancer and liver-related deaths.9. What Should I do if I Miss a Dose of Entercavir Hydrate?If you miss a dose of Entercavir Hydrate 209216-23-9, take it as soon as you remember. However, if the time is close to the next dose, skip the missed dose and continue with your regular dosing schedule. Do not double your dose.Entercavir Hydrate 209216-23-9, Benefits of Entercavir Hydrate, Uses of Entercavir Hydrate, Side Effects of Entercavir Hydrate, Precautions with Entercavir Hydrate Entercavir Hydrate 209216-23-9: Benefits, Uses and Side Effects Entercavir Hydrate 209216-23-9 is an effective drug used for the treatment of Hepatitis B. Learn about its benefits, uses, possible side effects and precautions here.Quote InquiryContact us!
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CAS: 114870-03-0 - The Synthetic Compound with Amazing Pharmaceutical Properties
CAS: 114870-03-0 - The Synthetic Compound with Amazing Pharmaceutical Properties
The Chemistry Behind CAS: 114870-03-0CAS: 114870-03-0 is a synthetic compound that is widely used in the pharmaceutical industry. It belongs to the class of compounds known as heterocyclic compounds, which are organic compounds that contain at least one hetero atom, such as nitrogen, in their ring structure.The Origin of CAS: 114870-03-0CAS: 114870-03-0 was first synthesized by a team of chemists at the pharmaceutical company Pfizer in 1989. The compound was initially developed as an anti-depressant, but was later found to have other therapeutic properties as well.The Chemical Properties of CAS: 114870-03-0CAS: 114870-03-0 has a chemical formula of C20H21ClN4O. It is a white to off-white crystalline powder that is insoluble in water. The compound has a molecular weight of 380.86 g/mol, and a melting point of 299-300 ℃.The Therapeutic Applications of CAS: 114870-03-0CAS: 114870-03-0 has a wide range of therapeutic applications. It has been found to be effective in the treatment of depression, anxiety disorders, obsessive-compulsive disorder, and panic disorder. It is also used in the treatment of neuropathic pain, chronic pain, and as a mood stabilizer for bipolar disorder.The Mode of Action of CAS: 114870-03-0CAS: 114870-03-0 works by inhibiting the reuptake of the neurotransmitter serotonin, which is responsible for regulating mood, sleep, appetite, and other bodily functions. By inhibiting the reuptake of serotonin, the compound increases the availability of the neurotransmitter in the brain, leading to an improvement in mood and a reduction in anxiety levels.The Precautions When Using CAS: 114870-03-0CAS: 114870-03-0 should be used with caution in patients with liver or kidney disease, as well as those with a history of seizures or a family history of bipolar disorder. The compound should not be used in combination with monoamine oxidase inhibitors (MAOIs), as this can lead to a dangerous increase in serotonin levels.The Future of CAS: 114870-03-0CAS: 114870-03-0 is a promising compound with a wide range of therapeutic applications. Ongoing research is focused on exploring its potential as a treatment for other conditions, such as post-traumatic stress disorder (PTSD), social anxiety disorder, and eating disorders.The ConclusionCAS: 114870-03-0 is a synthetic compound that has amazing pharmaceutical properties and is widely used in the treatment of depression, anxiety, and other disorders. The compound works by inhibiting the reuptake of serotonin, leading to an improvement in mood and a reduction in anxiety levels. Despite its side effects and precautions, CAS: 114870-03-0 remains a vital tool in the fight to improve mental health.Quote InquiryContact us!
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182182-31-6 | Exatecan Intermediate: Properties, Uses and Applications
182182-31-6 | Exatecan Intermediate: Properties, Uses and Applications
182182-31-6 | Exatecan Intermediate| Exatecan Intermediate: Properties, Uses and ApplicationsThe chemical compound 182182-31-6, also known as Exatecan intermediate, is a key component in the synthesis of a drug used for the treatment of different types of cancer. This article explores the properties, uses, and applications of this important chemical compound.Chemical Properties of 182182-31-6182182-31-6 is a pale yellow solid substance and belongs to the family of organic compounds known as quinoline alkaloids. It has a molecular weight of 471.524 g/mol and a melting point of 148-149 degrees Celsius.Applications of 182182-31-6182182-31-6 is mainly used as an intermediate in the synthesis of various compounds, especially the synthesis of Exatecan mesylate, which is a cytotoxic anticancer drug belonging to the non-camptothecin family of topoisomerase I inhibitors. This intermediate is a vital component in the synthesis of drugs used to treat ovarian cancer, colon cancer, and other types of solid tumors.Synthesis of Exatecan MesylateExatecan Mesylate, also known as DX-8951f, is used to treat a variety of malignant tumors. It is synthesized from 182182-31-6 through a multi-step process that involves several chemical reactions. At each stage, the product is purified to remove impurities and obtain the intermediate product, which is used in the next reaction step.Drug FormulationExatecan Mesylate is formulated as a sterile lyophilized powder and is administered through injection. The exact dosage and protocol depend on the patient, the cancer type, and other factors. It works by inhibiting DNA topoisomerase I and, thus, interfering with DNA synthesis and repair, eventually leading to the cancer cell's death.Side EffectsExatecan Mesylate is a potent cytotoxic agent that affects both normal and cancer cells. As such, it has many potential side effects, which may include nausea, vomiting, hair loss, fatigue, low blood cell count, fever, and others. Patients taking Exatecan Mesylate are closely monitored to identify any adverse reactions.ToxicityThe toxicity of 182182-31-6 varies depending on the exposure level and duration. In general, it is considered harmful when ingested or inhaled in high concentrations. Exposure to 182182-31-6 can lead to respiratory problems, skin irritation, and other health issues. As such, it needs to be handled with care, following the appropriate safety procedures and guidelines.Storage182182-31-6 should be stored in a cool, dry, and well-ventilated area. It should also be kept away from sources of ignition, heat, and direct sunlight. The compound is stable under normal conditions but may degrade when exposed to moisture or light.Environmental ImpactThe environmental impact of 182182-31-6 is not yet fully understood. As an organic compound, it may have potential effects on the environment if released into the soil or water supplies. However, the compound's impact is likely to be minimal, given its low toxicity and relatively low usage levels.Regulations182182-31-6 is not considered a controlled substance by most countries, but it may be subject to different regulatory standards in various jurisdictions. As such, users and suppliers are advised to follow the relevant guidelines and regulations to ensure the safe handling and use of the compound.Summary182182-31-6 is a key intermediate in the synthesis of Exatecan Mesylate, a potent cytotoxic anticancer drug used to treat a variety of tumors. It has many potential applications in the pharmaceutical industry and is an essential building block for many other compounds. While it has some toxicity and environmental impact concerns, it is generally considered safe when handled correctly and following appropriate regulations and guidelines.Quote InquiryContact us!
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CAS 169869-90-3 Exatecan Mesylate: A Comprehensive Guide
CAS 169869-90-3 Exatecan Mesylate: A Comprehensive Guide
IntroductionCAS 169869-90-3 Exatecan Mesylate is a drug used in cancer therapy. It belongs to the class of drugs called topoisomerase I inhibitors and it works by inhibiting the function of an enzyme called topoisomerase I, which is essential for DNA replication and cell proliferation. In this article, we will look at the various aspects of CAS 169869-90-3 Exatecan Mesylate.Chemical Properties of CAS 169869-90-3 Exatecan MesylateCAS 169869-90-3 Exatecan Mesylate is a semi-synthetic derivative of camptothecin, which is a natural alkaloid. Its chemical formula is C31H28N2O10S and its molecular weight is 640.63 g/mol. It is a pale yellow crystalline powder that is soluble in DMSO, ethanol, and methanol.Medical Uses of CAS 169869-90-3 Exatecan MesylateCAS 169869-90-3 Exatecan Mesylate is used in the treatment of various types of cancer, including ovarian cancer, lung cancer, and leukemia. It is administered through intravenous infusion and its dosage depends on the patient's weight and overall health.Mechanism of Action of CAS 169869-90-3 Exatecan MesylateCAS 169869-90-3 Exatecan Mesylate works by binding to and inhibiting the activity of topoisomerase I, an enzyme that is crucial for DNA replication and cell division. By inhibiting this enzyme, the drug prevents cancer cells from dividing and growing.Side Effects of CAS 169869-90-3 Exatecan MesylateLike all drugs, CAS 169869-90-3 Exatecan Mesylate has some side effects. The most common side effects include nausea, vomiting, diarrhea, fatigue, and weakness. Other less common side effects include anemia, neutropenia, thrombocytopenia, and liver toxicity.Precautions and ContraindicationsCAS 169869-90-3 Exatecan Mesylate should not be used in patients who are allergic to it or to any of its components. It should also be used with caution in patients with liver or kidney problems and in pregnant or breastfeeding women.Drug InteractionsCAS 169869-90-3 Exatecan Mesylate can interact with various medications, such as warfarin, dexamethasone, and phenytoin. It is crucial to notify the doctor of all medications the patient is currently using prior to beginning treatment with this drug.StorageCAS 169869-90-3 Exatecan Mesylate should be stored in a cool, dry place, away from direct sunlight and heat. It should also be kept out of the reach of children.ConclusionCAS 169869-90-3 Exatecan Mesylate is a potent drug used in cancer therapy. It works by inhibiting the activity of topoisomerase I, an enzyme that is essential for DNA replication and cell division. While it is generally well-tolerated, it can cause some side effects and should be used with caution in certain patients.Quote InquiryContact us!
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2212021-83-3 - Orforglipron Intermediate: A Comprehensive Guide
2212021-83-3 - Orforglipron Intermediate: A Comprehensive Guide
2212021-83-3 - Orforglipron intermediate: A Comprehensive GuideIf you are working in the pharmaceutical industry or any related field, there’s a good chance that you’ve come across the term "2212021-83-3 - Orforglipron intermediate". This term refers to a key intermediate compound that is used in the synthesis of Orforglipron, an important drug used in diabetes treatment. In this article, we will take a closer look at this compound and its significance in the production of Orforglipron.What is Orforglipron?Orforglipron is a drug that belongs to the class of thiazolidinediones, which are used to treat type 2 diabetes. The drug works by improving the body's response to insulin and lowering blood sugar levels. Orforglipron has been found to be effective in reducing the risk of cardiovascular disease in diabetic patients. The synthesis of Orforglipron involves several steps, and 2212021-83-3 is a key intermediate compound in this process.What is 2212021-83-3?2212021-83-3 is a chemical compound that is used in the synthesis of Orforglipron. It is a white to pale yellow powder that is soluble in organic solvents such as dimethyl sulfoxide and methanol. It has a molecular weight of 281.33 g/mol and a molecular formula of C12H11NO4S.Significance of 2212021-83-3 in Orforglipron Synthesis2212021-83-3 is a key intermediate compound in the synthesis of Orforglipron. It is used in the process of converting the starting material, which is 3-bromo-4-fluorobenzaldehyde, into the final product, Orforglipron. The compound undergoes several reactions, including a Grignard reaction and an S-alkylation reaction, which lead to the formation of Orforglipron.Synthesis of 2212021-83-3The synthesis of 2212021-83-3 involves several steps, starting from 2-hydroxy-phenylacetic acid. The acid is first converted into the corresponding ester, which is then subjected to bromination using N-bromosuccinimide. The resulting bromo ester undergoes a nucleophilic substitution reaction with p-fluoroaniline in the presence of potassium carbonate to form the desired product, 2212021-83-3.Properties of 2212021-83-32212021-83-3 is a stable compound that is relatively easy to handle in the laboratory. It has a melting point of around 160°C and a boiling point of about 360°C. The compound is sensitive to moisture and should be stored in a dry and well-ventilated area.Applications of 2212021-83-32212021-83-3 is primarily used as an intermediate compound in the synthesis of Orforglipron. However, it may also find applications in other areas such as agrochemicals and pharmaceuticals. The compound has been found to possess antimicrobial activity and could be used as a lead compound for the development of new drugs.Safety ConsiderationsWhen working with 2212021-83-3, it is important to take the necessary safety precautions. The compound may cause skin and eye irritation and could be harmful if ingested. It should be handled in a well-ventilated area, and appropriate personal protective equipment should be worn. The compound should be stored in a secure location away from children and animals.Conclusion2212021-83-3 is a key intermediate compound in the synthesis of Orforglipron, an important drug used in diabetes treatment. The compound undergoes several reactions to produce the final product. It has found applications in other areas such as agrochemicals and pharmaceuticals and possesses antimicrobial activity. When handling 2212021-83-3, it is important to take the necessary safety precautions.Quote InquiryContact us!
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