Nantong Noatic Bio-pharm Technology is an experienced supplier in China, specializing in the manufacturing of chemical drugs. Our product series, Isavuconazole, is widely acclaimed for its exceptional quality and effectiveness. With a focus on innovation and advanced technology, we bring forth a range of Isavuconazole products that are trusted by medical professionals worldwide. Isavuconazole offers numerous advantages, including superior efficacy, minimal side effects, and high patient tolerance. It finds extensive applications in the treatment of various fungal infections, providing relief and recovery to patients. Trust Nantong Noatic Bio-pharm Technology for all your Isavuconazole requirements, and experience the difference we bring to the pharmaceutical industry.
Isavuconazole is a triazole antifungal with broad spectrum of activity and good safety profile. It is approved by the FDA and EMA for treating invasive aspergillosis and mucormycosis. It works by inhibiting fungal cell membrane synthesis. Invasive fungal infections pose significant clinical challenges for patients, especially those who are immunocompromised. In vitro, most of the Candida species, most Aspergillus species, Mucorales, Cryptococcus spp., Fusarium species, dermatophytes and dimorphic fungi displayed susceptibility to isavuconazole. Resistance to isavuconazole has been associated with the mutation in the target gene CYP51. Cross-resistance between isavuconazole and other azoles was also proposed although the clinical relevance is unclear.