Introduction
182182-31-6 | Exatecan Intermediate| Exatecan Intermediate is a popular chemical that has been used as a synthetic intermediate in the drug manufacturing industry. It is most commonly used as a starting material for exatecan mesylate, a drug that has been found useful in cancer treatment.
What is 182182-31-6 | Exatecan Intermediate?
182182-31-6 | Exatecan Intermediate is a chemical compound with the molecular formula C25H26N2O4. Its systematic name is 4-oxo-1H-pyrrolo[3,2-c]quinoline-3-carboxylic acid methyl ester. It is typically produced by the condensation of 2-quinolinecarboxylic acid with 3-amino-2-methylbenzoic acid.
Applications
182182-31-6 | Exatecan Intermediate is an important intermediate compound in the synthesis of various drug molecules that have potential applications in cancer treatment. It is most notably used in the production of exatecan mesylate, which is a drug that has shown remarkable effectiveness in the treatment of various types of cancer, including lung, breast, and ovarian cancer.
Synthesis of Exatecan Mesylate
Exatecan mesylate is synthesized from 182182-31-6 | Exatecan Intermediate by treating it with various reagents in a complex multi-step reaction. Exatecan mesylate is the final product, which is obtained after purifying and isolating it from the reaction mixture. The yield of exatecan mesylate obtained using 182182-31-6 | Exatecan Intermediate as the starting material is high, making it a preferred choice in large-scale drug production facilities.
Properties
182182-31-6 | Exatecan Intermediate is a pale yellow solid that is slightly soluble in water. It is highly soluble in organic solvents, such as methanol and acetonitrile. It has a molar mass of 418.48 g/mol and a melting point of 225°C. It is an intermediate product in the exatecan mesylate synthesis reaction and has no significant biological activity of its own.
Stability and Storage
182182-31-6 | Exatecan Intermediate should be stored in a cool, dry place away from direct sunlight. It is sensitive to air and moisture, and contact with either can result in degradation of the compound. It should be stored in an airtight container and under a blanket of inert gas, if possible, to prevent degradation. The shelf life of this compound is typically one year when stored under ideal conditions.
Regulatory Status
182182-31-6 | Exatecan Intermediate is a non-regulated substance and does not have any mandatory reporting requirements under the various chemical regulatory regimes. However, it is always important to comply with local regulatory requirements and follow appropriate safety protocols for handling chemicals.
Conclusion
182182-31-6 | Exatecan Intermediate is an important chemical intermediate in the drug manufacturing industry, particularly in the production of exatecan mesylate. It has various potential applications in cancer treatment and other therapeutic areas. Proper handling and storage of this substance are crucial to maintain its stability and quality.