Synthetic Overview of [CAS No. 110351-94-5] Exatecan Intermediate
[CAS No. 110351-94-5] Exatecan Intermediate, a synthetic derivative of camptothecin, is widely used as an intermediate in preparing Exatecan mesylate, the anti-tumor drug. This intermediate is a key precursor used during the synthesis of Exatecan mesylate, which helps in treating various cancer types such as ovarian, prostate, lung, and breast cancer. Moreover, it improves the broader application scope of anticancer therapies.
Chemical Properties of [CAS No. 110351-94-5] Exatecan Intermediate
The formula of [CAS No. 110351-94-5] Exatecan Intermediate is C26H28N2O5, with a molecular weight of 464.515 g/mol. Moreover, it's a white crystalline powder with a melting point of 216.2 °C – 217.8 °C, and a boiling point of 670.5°C at 760 mmHg. Furthermore, it's insoluble in water but soluble in DMSO, methanol, and chloroform.
Potential Side Effects of [CAS No. 110351-94-5] Exatecan Intermediate
The use of [CAS No. 110351-94-5] Exatecan Intermediate as an intermediate in the preparation of anti-tumor drugs has some potential side effects such as nausea, anemia, and vomiting. In addition, it may lead to further side effects, including fatigue, diarrhea, and hair loss. Therefore, people are advised to take this compound under the supervision of a qualified doctor.
Usage of [CAS No. 110351-94-5] Exatecan Intermediate
[CAS No. 110351-94-5] Exatecan Intermediate is primarily used to prepare Exatecan mesylate, which is an anti-tumor drug used in different cancer types. This anti-tumor drug works by inhibiting the growth and replication of neoplastic target cells and brings various positive pharmacological responses. Moreover, this drug is indicated by healthcare practitioners for the treatment of various advanced and metastatic cancer types.
Applications of [CAS No. 110351-94-5] Exatecan Intermediate
[CAS No. 110351-94-5] Exatecan Intermediate is widely used in the commercial and medical industry for producing Exatecan mesylate, its derivative, an effective anti-cancer drug. Additionally, the broad-spectrum anticancer activity of this drug has made it an integral part of the pharmaceutical and medical industries. It is an essential compound for improving cancer treatment and promoting the overall health of patients.
Preparation Process of [CAS No. 110351-94-5] Exatecan Intermediate
The preparation of [CAS No. 110351-94-5] Exatecan Intermediate involves several steps. These steps include the bisheteroannulation reaction of (E)-N-(1-cyano-1-methoxyimino-2-butenyl)-2,3,4,9-tetrahydro-1H-carbazole-6-carboxamide, which is reacted with N,N-dimethyl-N'-methylthioformamidine under the influence of a catalyst. This process results in the formation of Exatecan Intermediate. The compound is then isolated using standard techniques to achieve the desired purity.
Future Scope of [CAS No. 110351-94-5] Exatecan Intermediate
The future of [CAS No. 110351-94-5] Exatecan Intermediate is bright, with increasing demand for anticancer drugs, the market growth of its derivatives, including Exatecan mesylate, is expected to increase rapidly in the coming years. Moreover, innovative drug development will benefit patients in the future by solving challenging medical conditions.
Conclusion
To sum up, [CAS No. 110351-94-5] Exatecan Intermediate is a synthetic compound and useful precursor, which is essential in the manufacturing of the anti-tumor drug Exatecan mesylate. With a broad-spectrum anticancer activity, Exatecan mesylate has various indications in the treatment of multiple cancer types. Moreover, with increasing market demand for anticancer drugs, the market growth of Exatecan mesylate is showing an upward trend in the pharmaceutical industry.