Introduction
CAS NO.2212020-52-3 is a chemical compound that is commonly known as Orforglipron API. It is widely used in the pharmaceutical industry as an active ingredient in various drugs. In this article, we will provide a comprehensive guide to Orforglipron API, covering various aspects related to the compound.
What is Orforglipron API?
Orforglipron API is a white or off-white crystalline powder that is soluble in water. The compound has a molecular weight of 433.44 g/mol and a chemical formula of C17H11ClF3N3O2S. It is a potent and selective inhibitor of dipeptidyl peptidase IV (DPP-IV), which is an enzyme that plays a crucial role in the regulation of glucose metabolism in the body.
Uses of Orforglipron API
Orforglipron API is primarily used in the pharmaceutical industry as an active ingredient in drugs that are used to treat type 2 diabetes. It works by inhibiting the activity of DPP-IV, which leads to increased levels of incretin hormones in the body. These hormones stimulate insulin secretion and reduce glucagon secretion, resulting in better glucose control in diabetic patients. In addition, Orforglipron API has also been shown to have potential therapeutic effects in other conditions such as Alzheimer's disease and some types of cancer.
Precautions and Side Effects
Orforglipron API is generally considered safe when used as directed. However, like all drugs, it can cause side effects in some people. The most common side effects include nausea, vomiting, diarrhea, abdominal pain, headache, and dizziness. In rare cases, the drug can cause more severe side effects such as pancreatitis and allergic reactions. It is important to consult a healthcare professional before using Orforglipron API to determine whether it is safe and appropriate for your individual needs.
Dosage and Administration
The dosage and administration of Orforglipron API may vary depending on the specific drug product that contains the compound. It is important to follow the instructions provided by the healthcare professional or manufacturer carefully. In general, Orforglipron API is taken orally once daily with or without food. The recommended starting dose is typically 5 mg per day, but this may be adjusted based on the individual's response to the drug.
Storage and Handling
Orforglipron API should be stored in a cool, dry place away from light and moisture. The compound should be handled with care, using appropriate safety measures such as gloves and protective clothing. It is important to follow all labeling and packaging instructions provided by the manufacturer to ensure proper storage and handling of the product.
Manufacturers and Suppliers
Orforglipron API is manufactured by various pharmaceutical companies around the world. Some of the leading manufacturers and suppliers of the compound include Merck KGaA, Chem-Impex International, VWR International, and Santa Cruz Biotechnology. It is important to choose a reputable and reliable supplier when sourcing Orforglipron API to ensure product quality and consistency.
Market Trends and Outlook
The market for Orforglipron API is expected to grow in the coming years, driven by the increasing prevalence of type 2 diabetes and the rising demand for effective and safe diabetes treatments. According to a report by Transparency Market Research, the global market for DPP-IV inhibitors, including Orforglipron API, is projected to reach USD 26.9 billion by 2022, growing at a CAGR of 8.5% from 2014 to 2022.
Conclusion
Orforglipron API is a potent and selective inhibitor of DPP-IV that is widely used in the pharmaceutical industry as an active ingredient in drugs for the treatment of type 2 diabetes. The compound has potential therapeutic effects in other conditions and is generally considered safe when used as directed. It is important to follow all precautions and instructions when handling and using Orforglipron API.
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