Introduction
2212021-83-3 - Orforglipron intermediate is a chemical compound commonly used in the pharmaceutical industry. This compound serves as an important intermediate for the synthesis of Orforglipron, a drug used to treat various bacterial infections. In this article, we will examine the various aspects of 2212021-83-3 - Orforglipron intermediate and its significance.
Chemical Properties
2212021-83-3 - Orforglipron intermediate is a crystalline solid with a molecular weight of 418.44 g/mol. It is sparingly soluble in water but dissolves well in organic solvents. This intermediate contains a carboxylic acid group and a pyrazole ring that are essential for the synthesis of Orforglipron.
Synthesis
The synthesis of 2212021-83-3 - Orforglipron intermediate involves several steps. The process begins with the reaction between 2,3-dimethyl-4-nitroquinolone and hydrazine hydrate to form 2,3-dimethyl-4-nitropyrazole. The nitro group in this compound is then reduced to an amino group to create 2,3-dimethyl-4-aminopyrazole. The final step involves the esterification of 2,3-dimethyl-4-aminopyrazole with ethyl 2-(2-chloroethyl)-4-methylthiazole-5-carboxylate to produce 2212021-83-3 - Orforglipron intermediate.
Uses
2212021-83-3 - Orforglipron intermediate is primarily used as a key intermediate in the synthesis of Orforglipron, which is a broad-spectrum antibiotic drug used to treat bacterial infections. Orforglipron is particularly effective in treating antibiotic-resistant strains of bacteria, including Methicillin-resistant Staphylococcus aureus (MRSA) and Vancomycin-resistant Enterococcus (VRE).
Safety
The safety of 2212021-83-3 - Orforglipron intermediate has not been extensively studied. However, it is important to handle this compound with caution as it is potentially hazardous. Avoid prolonged exposure to this compound and take appropriate safety measures when handling it.
Storage
2212021-83-3 - Orforglipron intermediate should be stored in a cool, dry place away from sources of heat and light. This compound should be kept in an airtight container to prevent contamination.
Conclusion
2212021-83-3 - Orforglipron intermediate is a crucial compound in the synthesis of Orforglipron, a potent antibiotic drug used to treat bacterial infections. With its unique chemical properties and synthesis method, this compound plays an essential role in the pharmaceutical industry.